Cancer is a breakdown of cell cooperation
Every human body is a symphony of multicellular cooperation. 30 trillion cells Working together and coordinating with each other, they make us viable multicellular organisms.
For multicellular coordination to work, cells must: serve the collectiveThese include controlled cell division, proper cell death, resource sharing, division of labor, and protection of the extracellular environment. Multicellular cooperation allows the body to function effectively. When genetic mutations prevent these proper behaviors, cell cooperation can be disrupted and cancer can develop.
A cancer cell can be thought of as follows. cell phone scammer Because they don’t follow the rules of cooperative behavior. They mutate uncontrollably, evading cell death and occupying excess resources at the expense of other cells. As these cheetah cells replicate, cancer in the body begins to grow.
Cancer is basically a problem of multiple cells living together in one organism.so it was around Since the origin of multicellular lifeThis means that cancer suppressor mechanisms have evolved for hundreds of millions of years to help keep cancer cells in check. known to induce cell death. Cells also monitor neighboring cells for evidence of abnormal behavior and signal abnormal cells to induce apoptosis. Additionally, the body’s immune system monitors tissues to destroy cancer cells.
Cells that can evade detection, avoid apoptosis, and replicate rapidly have an evolutionary advantage in the body over normally functioning cells.This process in the body called evolution of the bodyis what causes cancer cells to multiply and make people sick.
Microbes can help or hinder cell cooperation
Microorganisms can affect cancer risk by changing the way the body’s cells interact with each other.
some microbes protect against cancer By maintaining a healthy environment in the gut, reducing inflammation and DNA damage, and even directly limiting tumor growth. Lactobacillus pentosus, Lactobacillus gasseri When Bifidobacterium bifidum It is found in the environment and various foods and can live in the intestine.these microorganisms Promotes cooperation between cells It limits the function of rogue cells by strengthening the body’s cancer defenses. lactobacillus acidophilus,for example, production of a protein called IL-12 It stimulates immune cells to act against tumors and suppress their growth.
Other microbes promote cancer by inducing mutations in healthy cells, making it more likely that cell impostors will emerge and defeat cooperating cells. Microorganisms that cause cancer like that Enterococcus faecalis, Helicobacter pylori When papillomavirus Associated with increased tumor burden and cancer progression. release toxins that damage DNA, alter gene expression, increase proliferation of tumor cells. Helicobacter pyloriFor example, it can induce cancer by secreting a protein called Tipα. This protein can penetrate cells, alter gene expression, and cause stomach cancer.
A Healthy Diet With Cancer-Protecting Microbes
What you eat determines the amount of cancer-inducing and cancer-preventing microbes in your body, so the microbes we consume and culture are: healthy eating.
Beneficial microbes are usually fermented A plant-based diet such as vegetables, fruits, yogurt, and whole grains. These foods are nutritious and contain microbes that boost the immune system’s ability to fight cancer and reduce overall inflammation. High fiber foods are prebiotics In the sense that it provides a resource that helps beneficial microbes thrive and subsequently benefit the host. Many cancer-fighting microbes are abundant in fermented and high-fiber foods.
In contrast, harmful microbes are found in highly processed meat-based diets. .Meat-based diet is associated with increased cancer prevalence, red meat carcinogenStudies have shown that a meat-based diet is associated with cancer-inducing microbes. Fusobacteria When peptostreptococcus both in humans and other species.
Microbes can enhance or interfere with how the body’s cells work together to prevent cancer. We believe that deliberately culturing a microbiome that promotes cell-to-cell cooperation can reduce cancer risk.
This article is reprinted from conversationis an independent, non-profit news site dedicated to sharing ideas from academic experts.There are many types of conversation Attractive free newsletter.
It was written by: Gissel Marquez Alcalaz, Arizona State University When Athena Actipis, Arizona State University.
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Gissel Viridiana Marquez Alcaraz is funded by the National Cancer Institute.
Athena Aktipis is funded by the National Cancer Institute and the John Templeton Foundation.
